The 9MP ABS standard on the 899 Panigale is a latest-generation system with two channels that performs combined braking with control of rear wheel lifting to guarantee not only shorter braking distances, but also the greatest stability during braking. Specifically intended for sport use, the 9MP ABS offers three levels of operation, each associated with a Riding Mode; in the Race mode, the system works only on front discs to allow advanced track braking techniques for expert riders.

The 899 Panigale uses black 10-spoke rims, 3.5 inches at front and 5.5 inches at rear, which due to their light weight allow rapid changes in direction and improved performance both on acceleration and during braking.